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两种方案治疗慢性乙型肝炎肝纤维化的成本-效果分析
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篇名: 两种方案治疗慢性乙型肝炎肝纤维化的成本-效果分析
TITLE:
摘要:

目的:评价两种治疗慢性乙型肝炎肝纤维化方案的成本-效果。方法:选择112 例慢性乙型肝炎肝纤维化患者随机分成

复方鳖甲软肝片组(A组)和安络化纤丸组(B组)各56 例,两组患者分别服用恩替卡韦分散片联合相应的中成药。分别在治疗

前后检测两组患者的肝纤维化指标、瞬时弹性成像,进行中医证候评分,计算有效率,比较两种方案的成本-效果。结果:A组方

案的成本为9 227.10 元,有效率为74.11%,成本-效果比为12 451;B组方案的成本为8 202.90 元,有效率为69.28%,成本-效果比

为11 840;增量成本-效果比为21 205。B组方案具有较好的成本-效果。敏感度分析结果与成本-效果分析结果一致。结论:安络

化纤丸联合恩替卡韦治疗慢性乙型肝炎肝纤维化的成本-效果优于复方鳖甲软肝片联合恩替卡韦。

ABSTRACT:

OBJECTIVE:To analyze the cost-effectiveness of two regimens in the treatment of chronic hepatitis B fibrosis.

METHODS:112 cases of chronic hepatitis B fibrosis were divided into Compound biejia ruangan tablet group(group A,n=56)

and Anluo huaxian pill group(group B,n=56). Both groups received Entecavir dispersible tablets combined with relevant Chinese

patent medicine. The liver fibrosis index and transient elastography of 2 group were detected before and after treatment,TCM symptom

score and effective rate calculation were conducted to compare the cost-effectiveness of 2 groups. RESULTS:The cost,effective

rate and cost-effectiveness ratio of group A were 9 227.10 yuan,74.11% and 12 451;those of group B were 8 202.90 yuan,

69.28% and 11 840;incremental cost-effectiveness ratio was 21 205. Group B showed a better cost-effectiveness. Result of sensitivity

test was same to that of cost-effectiveness analysis. CONCLUSIONS:The cost-effectiveness of Anluo huaxian pill combined

with Entecavir dispersible tables is better than Compound biejia ruangan tablet combined with Entecavir dispersible tables in the

treatment of chronic hepatitis B fibrosis.

期刊: 2015年第26卷第35期
编辑: 王沛陵,李晶莹,付娜,段小宛
AUTHORS: WANG Pei-ling,LI Jing-ying,FU Na,DUAN Xiao-wan
关键字: 复方鳖甲软肝片;安络化纤丸;乙型肝炎肝纤维化;成本-效果分析
KEYWORDS: Compound biejia ruangan tablet;Anluo huaxian pill;Chronic hepatitis B fibrosis;Cost-effectiveness analysis
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