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我院外科2013-2014年参附注射液使用分析
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篇名: 我院外科2013-2014年参附注射液使用分析
TITLE:
摘要: 目的:了解参附注射液 (SFI) 在我院外科临床应用情况,为合理使用SFI提供参考。方法:采用回顾性研究的方法,选取我院医院信息系统(HIS)中2013年1月-2014年12月外科使用SFI患者的一般情况、适应证、用法用量、疗程、合并用药等资料,进行统计分析,同时监测药品不良反应(ADR)/事件(ADE)的发生情况。结果:1 247例使用SFI的外科住院患者,分布在甲状腺乳腺外科(634例)、综合微创外科(292例)、胃肠外科(250例)、泌尿外科(64例)和胸心外科(7例)5个病区,其中男性466例,女性781例,男女比例为1 ∶ 1.68;平均年龄58.50岁;主要用于围术期(78.11%)和肿瘤(11.23%);疗程多集中在2~7 d(71.45%);剂量多为100 ml(70.01%);合并用药主要为泮托拉唑钠、鸦胆子油乳注射液和注射用血栓通(冻干)等。在适应证、用量、溶剂选择、用药频次和合并用药等方面均存在不规范现象。未发现与SFI明显相关的ADR/ADE。结论:SFI在我院外科临床的不合理使用须引起重视;临床应正确认识中药注射剂的临床安全使用问题,做到辨证施治、合理用药。
ABSTRACT: OBJECTIVE: To know the utilizatior of Shenfu injection (SFI) in our hospital, and provide reference for rational use of SFI. METHODS: In respective study, patients received SFI from the Hospital Information System (HIS) in surgery department in our hospital from Jan. 2013 to Dec. 2014 were analyzed statistically in aspects of general situation, indications, usage and dosage, course of treatment, drug combination, etc. And the incidence of ADR/ADE was monitored. RESULTS: The 1 247 surgery inpatients used SFI distributed in thyroid and galactophore department (634 cases), comprehensive minimally invasive department (292 cases), gastrointestinal surgery department (250 cases), urology department (64 cases) and cardiothoracic surgery department (7 cases), including 466 male and 781 female, the ratio of male to female was 1 ∶ 1.68, average age was 58.50 years; it mainly used in perioperative medication (78.11%) and treated for tumors (11.23%), treatment course concentrated on 2-7 d (71.45%), dosage mainly was 100 ml (70.01%); combination medication were mainly pantoprazole sodium, Fructus bruceae injection, Xueshuantong for injection (lyophilized), etc. The nonstandard phenomenon was existed in indications, dosage, solvent selection, medication frequency, drug combination, etc. There were no obvious ADR/ADE related to SFI. CONCLUSIONS: More attention must be paid to the irrational use of SFI in surgery clinic of our hospital, the safety of traditional Chinese medicine injection in clinical use should be correctly understood, achieve dialectical therapy and rational drug use.
期刊: 2016年第27卷第26期
编辑: 吴文,尹克鑫,范鲁雁
AUTHORS: WU Wen,YIN Kexin,FAN Luyan
关键字: 参附注射液;外科;用药分析;合理用药
KEYWORDS: Shenfu injection; Surgery; Analysis of medication; Rational drug use
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